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The Sinclair Method (TSM) is a highly effective, scientifically validated protocol for treating alcohol use disorder that has a profound Finnish connection, though with a slight nuance. It was discovered by an American scientist, Dr. David Sinclair, while conducting decades of research at Alko (the Finnish state-owned alcohol company’s research laboratories) and the Finnish National Public Health Institute. [1, 2, 3]

Rather than requiring immediate, absolute abstinence, TSM uses a “targeted medication” approach. A person takes an opioid antagonist medication, such as Naltrexone, one hour before consuming alcohol. The medication blocks the endorphin reward system in the brain, gradually causing “pharmacological extinction”—meaning the brain unlearns the compulsion to drink heavily over time. Clinical studies show an impressive 78% success rate in helping individuals either return to safe, controlled drinking or stop entirely.